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NCI-H460 Cell Line

NCI-H460 is a tumorigenic cell line that was established in 1982 from the lung tissue pleural fluid of a male patient with large cell lung carcinoma. NCI-H460 cells exhibit an epithelial morphology and adherent cultural properties. The NCI-H460 cell line is also hypotriploid and has a modal chromosome number of 57. NCI-H460 cells express p53 mRNA at levels similar to those of normal lung tissue and stain positively for kertain and vimentin. NCI-H460 is a suitable transfection host and an  NCI-H460 transfection kit can be purchased from Altogen Biosystems to conduct lung cancer research.
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Altogen Lung Xenografts for Biomedical Studies

Altogen Biosystems is a recognized developer and laboratory for biological laboratories. Custom research offers and additional preclinical items include xenografts, toxicology assays, 28-day generation of stably-transfected cells, liposome encapsulation and more. Dedicated to assisting pharmaceutical companies with cutting-edge and excellent services, Altogen Biosystems endeavors to optimize modern laboratory technologies. Visit Altogen’s website for a list of lung xenograft models .
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NCI-H460 Cells for Lung Cancer Research

Derived nearly 40 years ago, the NCI-H460 cell line has a few unique characteristics that have made it one of the principal cell lines used in lung cancer research. NCI-H460 cells do not have significant damage to DNA, and they express normal amounts of p53 mRNA, making their proliferation somewhat of a mystery and a path towards discovering complex cell proliferation and tumorigenesis pathways. In terms of gene therapies to combat late-stage lung cancer, transfection reagents that are not cytotoxic can show how the large-cell carcinoma that is the NCI-H460 cell line responds to changes in its genome, possibly discovering novel manners of curing lung cancer even after late diagnosis.
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NCI-H460 Transfection Reagent (Lung Carcinoma, HTB177)

In 1982 the NCI-H460 cell line was discovered using the cells of a male patient with large cell lung carcinoma. These cells exhibit epithelial cellular morphology, are tumorigenic and express p53 mRNA similar to normal lung cells. This tumorigenic cell line is particularly unique in that it expresses no different structural DNA abnormalities, and its modal chromosome number of 57 makes it ideal for lung cancer research.  The NCI-H460 cell line is typically used in molecular and biomedical lung cancer research. Altogen Biosystems manufactures a high efficiency lipid-based transfection reagent to facilitate these studies.  Transfection Reagent for NCI-H460 Cells (Lung Carcinoma Cells, HTB-177)
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